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Integral Molecular 是一家研究驅(qū)動(dòng)的生物技術(shù)公司,為未充分利用的膜蛋白靶標(biāo)創(chuàng)造創(chuàng)新技術(shù)和治療性抗體,包括 GPCR、離子通道、轉(zhuǎn)運(yùn)蛋白和病毒包膜。公司使命是開(kāi)發(fā)和應(yīng)用創(chuàng)新技術(shù),推動(dòng)針對(duì)困難蛋白質(zhì)靶標(biāo)的治療發(fā)現(xiàn)。 憑借 20 多年專注于膜蛋白和抗體的經(jīng)驗(yàn),我們的技術(shù)已為 400 多家從事研究、藥物發(fā)現(xiàn)和疫苗開(kāi)發(fā)的公司提供支持。
Integral Molecular針對(duì)復(fù)雜膜蛋白(包括 GPCR、離子通道、轉(zhuǎn)運(yùn)蛋白和病毒蛋白)分離 MAb 的成功率為 95%,并且在分離和表征復(fù)雜膜蛋白方面擁有 15 年以上的經(jīng)驗(yàn)。Integral Molecular脂質(zhì)體代理
Integral Molecular產(chǎn)品列表:Integral Molecular脂質(zhì)體代理
種類 | 受體 | 名稱 | 貨號(hào) |
GPCR | A2AR | Alpha Adrenergic | RR-0910 |
B2AR | Beta Adrenergic | RR-0574 | |
CCR1 | Chemokine | RR-0968 | |
CCR2b | Chemokine | RR-0125 | |
hCCR5 | Chemokine | RR-0190 | |
mCCR5 | Chemokine | RR-0835 | |
rhCCR5 | Chemokine | RR-0895 | |
CCR6 | Chemokine | RR-0822 | |
CCR10 | Chemokine | RR-0193 | |
CXCR2 | Chemokine | RR-0943 | |
CXCR3 | Chemokine | RR-0132 | |
CXCR4 | Chemokine | RR-0830 | |
CXCR7 | Chemokine | RR-0656 | |
mCXCR4 | Chemokine | RR-2194 | |
GLP-1R | Glucagon-like peptide-1 Receptor | RR-1090 | |
GCGR | Glucagon Receptor | RR-0999 | |
GAL1 Receptor | Neuropeptide Receptor | RR-1067 | |
5-HT2C | Serotonin Receptor | RR-1498 | |
FZD4 | Wnt Pathway | RR-1302 | |
Ion Channel | HV1 | Voltage Gated H+ | RR-0678 |
TRPC4 | Nonspecific Cation Channel | RR-1054 | |
TRPM4 | Nonspecific Cation Channel | RR-1333 | |
K2P1.1 | Potassium Channel | RR-1225 | |
K2P4.1 | Potassium Channel | RR-1331 | |
P2X2 | ATP Purinoceptor | RR-1181 | |
Transporter | GLUT1 | Glucose Transporter | RR-0777 |
RTK | ALK2 | Activin Receptor | RR-0850 |
1-TM
1-TM | ACVR1 | Activin A Receptor,Type I | RR-0850 |
CD19C | B-Cell Activation | RR-0553 | |
CD27C | B-Cell Activation | RR-0655 | |
DC-SINGC | Lectin | RR-0057 | |
DC-SINGR | Lectin | RR-0056 | |
LRP6C | Wnt Pathway | RR-0853 | |
hTL1A | TNF Ligand | RR-0819 | |
mTL1A | TNF Ligand | RR-0817 | |
ST2L | IL-1 Receptor Familly | RR-0653 | |
4-TM | CD81 | Hepatitis C Attachment | RR-0341 |
CD20 | B-Cell Activation | RR-1179 | |
Claudin-1 | Tight Junction | RR-0825 | |
Claudin-2 | Tight Junction | RR-0733 | |
Claudin-3 | Tight Junction | RR-0686 | |
Viral Protein | RSV-F | Respiratory Syncytial Virus | RR-0891 |
Influenza M2 A/Udorn/307/1972 | Ion Channel | RR-0929 | |
Influenza M2 A/HK/156/1997 | Ion Channel | RR-0179 | |
Chikungunya Virus | Viral Envelope | RR-0945 | |
Ross River Virus | Viral Envelope | RR-1136 |